Detective William Murdoch (Yannick Bisson, Sue Thomas: F.B.Eye) and his friends face new challenges in Edwardian Toronto as the award-winning Canadian mystery returns. With Murdoch languishing in jail for murder, Constable Crabtree (Jonny Harris, Still Standing), Inspector Brackenreid (Thomas Craig, Coronation Street) , and Detective Watts (Daniel Maslany, Goliath) race to prove his innocence, while Dr. Julia Ogden (Gemini winner Hélène Joy, Durham County) remains in hiding from the corrupt forces that have taken over Station House No. 4.
When the dust settles, Murdoch and his team solve cases featuring poisoned wine, high-speed transportation, botched organ transplants, and anti-Semitic riots, along the way encountering historical figures like Helen Keller, Alexander Graham Bell, and Theodore Roosevelt. Guest stars include Tamzin Outhwaite (New Tricks), Colin Mochrie (Whose Line Is It Anyway?), Peter Keleghan (Workin’ Moms), David Hewlett (The Shape of Water), and WWE Raw and Smackdown! star Jay “Christian” Reso.